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- Title
Urinary Tract Infections in Elderly: Uropathogen and Drug Sensitivity Profile.
- Authors
Ben George, Thomson; Shubhangi, Kanitkar; Reddy, Prodduturu Priyanka; Surendrakumar, Mankoskar Yash; Srikanth, Gonipati Lakshmi
- Abstract
Background: With the ever-increasing geriatric population and the challenging nature of treatment of these patients, knowledge of pathogens and empirical medication to be offered helps improve patient outcome. This study was done with the objective of identifying the uropathogens and their drug sensitivity profile, in elderly patients admitted to a tertiary hospital in western India. Method: All in-patients aging 60 years and above, having symptoms suggestive of urinary tract infection were chosen. Information regarding patients were recorded on a pre structured proforma after taking their informed consent. Only patients with significant growth of organisms on microbiological analysis were included in the final study. Results: Of the 50 participants of the study, Gram negative organisms were isolated from 90% of the urine cultures; E.coli being the most common; followed by Klebsiella; Pseudomonas; Citrobacter and Proteus. Among the 10% of gram positive organisms, isolated organisms included Enterococcus species and S.aureus. The overall culture sensitivity pattern showed that most of the organisms were sensitive to Meropenem and Gentamycin (72%) followed by Amikacin(70%); Ceftazidime Tazobactum and Piperacillin Tazobactum (58% each); Amoxicillin Clavulanic Acid (54%) and Ceftazidime(50%). Sensitivity to the commonly used anti-microbials like Ceftriaxone, Cotrimoxazole and fluoroquinolones was very low. Conclusion: Availability and knowledge of local antibiograms especially in resource poor settings or in the event that culture reports are unavailable to initiate empirical therapy allow for improved treatment outcomes.
- Subjects
INDIA; GRAM-negative bacteria; MEROPENEM; OLDER patients; OLDER people; URINARY tract infections; PIPERACILLIN; ENTEROCOCCAL infections
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2021, Vol 12, Issue 1, p224
- ISSN
0975-3583
- Publication type
Article
- DOI
10.31838/jcdr.2021.12.01.36