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- Title
Construction of specific nickel-based electrode using N,N-dimethylformamide/ water as solvent and the application in metronidazole detection.
- Authors
Yunfan Lu; Ruibin Wang; Guoping Wang; Nian Chen
- Abstract
To achieve rapid detection for metronidazole (MNZ), a mesoporous nickel-based metal–organic framework (Ni-MOF), which had sub-micron-assemblies of layered flakes and abundant carboxyl groups, was synthesized in a particular solvent containing water with a facile one-step hydrothermal method. Using Ni-MOF/multi-walled carbon nanotubes as the sensor electrode, cyclic voltammetry and differential pulse voltammetry were investigated in MNZ solution (containing 0.1 M PBS). The current response linearly varied with MNZ’s concentration in the range of 5–100 µM. A relatively low detection limit of 25 nM was obtained, which outperformed many electrochemical platforms for MNZ reported in literatures. Moreover, further investigations indicated this system was endowed with good anti-interference ability repeatability, and long-term stability. The present work was promising to pave the way for the quantitation of MNZ in biomedical and healthcare applications.
- Subjects
METRONIDAZOLE; WATER use; METAL-organic frameworks; CYCLIC voltammetry; CARBON nanotubes
- Publication
Desalination & Water Treatment, 2023, Vol 293, p150
- ISSN
1944-3994
- Publication type
Article
- DOI
10.5004/dwt.2023.29529